Cassette exon inclusion is represented as a ratio of expression
for transcripts which include a specific exon
to all those transcripts which could have possibly included it.
Numerators and denominators of these ratios are stored in a tab-separated format (TSV) table
in order to still enable TPM-based filtering
Each row in the expression table represents a single cassette exon. The first column
specifies exon coordinates in a BED format.
Each of the next columns stores TPM values for
specific RNA-Seq samples. Columns with numerators of the inclusion fraction ratios are
denoted with an "_included" suffix whereas denominators are marked with "_total".
Please see the scheme below:
|
Sample1_included |
Sample2_included |
... |
Sample1_total |
Sample2_total |
... |
| Exon1 |
|
|
|
|
|
|
| Exon2 |
|
|
|
|
|
|
| Exon3 |
|
|
|
|
|
|
| ... |
|
|
|
|
|
|
